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KMID : 1225720200120020364
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Allergy, Asthma & Immunology Research : AAIR
2020 Volume.12 No. 2 p.364 ~ p.370
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Primary Nasal Epithelial Cells From Allergic and Non-allergic Individuals Show Comparable Barrier Function
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Waltl Eva E.
Stanek Victoria
Mueller Christian A.
Kiss Renata
Eckl-Dorna Julia
Valenta Rudolf
Niederberger Verena
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Abstract
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Previous reports suggested that ex vivo cultured primary nasal epithelial cells from allergic patients differ from those from non-allergic individuals by genuinely reduced barrier function. By contrast, we found that primary nasal epithelial cells from allergic and non-allergic individuals showed comparable barrier function and secretion of cytokines.
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KEYWORD
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Respiratory epithelial barrier function, allergic rhinitis, allergen, immunoglobulin E, allergen-microarray, transepithelial resistance
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